NEW PERSPECTIVES IN THE STRUCTURAL APPROACH OF GENETIC DISEASES: STRUCTURAL STUDIES ON FRATAXIN, THE PROTEIN RESPONSIBLE FOR FRIEDREICH ATAXIA.

Pubblicazioni Scientifiche

• BIOCHEMISTRY

  The long acidic tail of high mobility group box 1 (HMGB1) protein forms an extended and flexible structure that interacts with specific residues within and between the HMG boxes

• BIOPHYSICAL JOURNAL

  Characterization of the protein unfolding processes induced by urea and temperature

• CHEMISTRY & BIOLOGY

  Glycyrrhizin binds to high-mobility group box 1 protein and inhibits its cytokine activities

• EMBO REPORTS

  The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

• FEBS LETTERS

  Nects of pathological mutations on the stability of a conserved amino acid triad in retinoschisin

• JOURNAL OF BIOLOGICAL CHEMISTRY

  Structural properties of Gerstmann-Straussler-Scheinker disease amyloid protein

• JOURNAL OF BIOLOGICAL CHEMISTRY

  NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1)

• NUCLEIC ACIDS RESEARCH

  Structural basis for PHDVC5HCHNSD1-C2HRNizp1 interaction: implications for Sotos syndrome

• PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

  Interactions of the C2 domain of human Factor V with a model membrane