GENERATION OF ANIMAL MODELS OF HUMAN GENETIC DISEASES ASSOCIATED WITH DLX GENES ALTERATIONS; DEVELOPMENT OF NEW NON-VIRAL GENE THERAPY APPROACHES

Pubblicazioni Scientifiche

• ANNALS OF NEUROLOGY

  PMP22 transgenic dorsal root ganglia cultures show myelin abnormalities similar to those of human CMT1A

• DEVELOPMENT

  Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5

• GENE THERAPY

  Rapid crossing of the pulmonary endothelial barrier by polyethylenimine/DNA complexes

• INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

  Multiple functions of Dlx genes

• JOURNAL OF DRUG TARGETING

  Optimisation of polyethylenimine-based gene delivery to mouse brain

• JOURNAL OF LEUKOCYTE BIOLOGY

  DLX genes as targets of ALL-1:: DLX 2,3,4 down-regulation in t(4;11) acute lymphoblastic leukemias

• MOLECULAR AND CELLULAR NEUROSCIENCE

  Preferential transfection of adult mouse neural stem cells and their immediate progeny in vivo with polyethylenimine

• NEUROBIOLOGY OF DISEASE

  The D355V mutation decreases EGR2 binding to an element within the Cx32 promoter