CLOSTRIDIAL NEUROTOXINS: MECHANISM OF ACTION AND THERAPEUTIC TREATMENT OF DISEASES OF THE NEUROMUSCULAR JUNCTION

Pubblicazioni Scientifiche

• CLINICA CHIMICA ACTA

  Bacterial toxins with intracellular protease activity

• JOURNAL OF CELL SCIENCE

  Functional characterisation of tetanus and botulinum neurotoxins binding domains

• JOURNAL OF NEUROCHEMISTRY

  Internalization and proteolytic action of botulinum toxins in CNS neurons and astrocytes

• JOURNAL OF NEUROCHEMISTRY

  Botulinum neurotoxin E-insensitive mutants of SNAP-25 fail to bind VAMP but support exocytosis

• JOURNAL OF NEUROCHEMISTRY

  Tetanus toxin fragment C binds to a protein present in neuronal cell lines and motoneurons

• NEUROSCIENCE LETTERS

  Different time courses of recovery after poisoning with botulinum neurotoxin serotypes A and E in humans

• PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

  Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses

• TOXICOLOGY LETTERS

  In vitro biological activity and toxicity of tetanus and botulinum neurotoxins

• TOXICON

  Tetanus and botulinum neurotoxins: turning bad guys into good by research

• TOXICON

  Active-site mutagenesis of tetanus neurotoxin implicates TYR-375 and GLU-271 in metalloproteolytic activity

• TRENDS IN BIOCHEMICAL SCIENCES

  How do presynaptic PLA2 neurotoxins block nerve terminals?