BIOLOGICAL CHARACTERIZATION AND GENE TRANSFER IN OTHER PRIMARY IMMUNODEFICIENCIES

Pubblicazioni Scientifiche

• AIDS

  Decreased apoptosis of bone marrow progenitor cells in HIV-1-infected patients during highly active antiretroviral therapy

• AIDS RESEARCH AND HUMAN RETROVIRUSES

  HIV type 1 protease inhibitors enhance bone marrow progenitor cell activity in normal subjects and in HIV type 1-infected patients

• AUTOIMMUNITY REVIEWS

  Immunodysregulation of HIV disease at bone marrow level

• BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

  Gene therapy for adenosine-deaminase-deficient severe combined immunodeficiency

• BLOOD

  SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cells

• CLINICAL AND EXPERIMENTAL IMMUNOLOGY

  Biased T-cell receptor repertoires in patients with chromosome 22q11.2 deletion syndrome (DiGeorge syndrome/velocardiofacial syndrome)

• CLINICAL CHEMISTRY

  Capillary electrophoresis in diagnosis and monitoring of adenosine deaminase deficiency

• HAEMATOLOGICA

  Efficient gene transfer into primitive hematopoietic progenitors using a bone marrow microenvironment cell line engineered to produce retroviral vectors

• JOURNAL OF CLINICAL INVESTIGATION

  Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells

• JOURNAL OF IMMUNOLOGY

  Bone marrow clonogenic capability, cytokine production, and thymic output in patients with common variable immunodeficiency

• JOURNAL OF IMMUNOLOGY

  Innate-like effector differentiation of human invariant NKT cells driven by IL-7

• MOLECULAR THERAPY

  Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction

• NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

  Evaluation of ADA gene expression and transduction efficiency in ADA/SCID patients undergoing gene therapy

• SCIENCE ADVANCES

  CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells

• TRENDS IN IMMUNOLOGY

  Beneficial autoimmunity in Type 1 diabetes mellitus